AIM-SAFE: a new European project awarded to DS4DH under the GenAI4EU call

We are pleased to announce that our group has been awarded a new project under the Horizon Europe GenAI4EU call "Leveraging multimodal data to advance Generative Artificial Intelligence applicability in biomedical research". AIM-SAFE — A Multi-Agent Framework for Safe, Specialised, and Adaptive Clinical Reasoning was initiated and structured by the DS4DH group and brings together a consortium of 25 institutions across 14 countries, with a total budget of €16.7 million (€1.73 million allocated to the Geneva teams). The project is co-led at the University of Geneva by Prof. Douglas Teodoro (Department of Radiology and Medical Informatics, Faculty of Medicine) and Prof. Caroline Samer (Director of the Department of Anaesthesiology, Pharmacology, Intensive Care and Emergency Medicine, and Head of the Division of Clinical Pharmacology and Toxicology at the HUG).

AIM-SAFE will develop a generative AI-based clinical decision support framework relying on specialised agents able to analyse complex biomedical data in order to predict adverse drug events, identify deprescribing opportunities, integrate pharmacogenomics into therapeutic decisions, and optimise dosing regimens — with a particular focus on polymedicated and oncology patients. Our group will lead the development of personalised predictive models, based on small language models and agentic technologies, for prescribers and clinical pharmacologists, while clinical validation across European hospitals will be coordinated by Prof. Samer together with Dr Aurélien Simona (HUG). Beyond its clinical ambitions, AIM-SAFE aims to contribute to a reliable, explainable and privacy-preserving European medical AI, fully compliant with the GDPR, the AI Act and the European Health Data Space.